Roberto P Garofalo Selected Research

Respiratory Syncytial Virus Infections

12/2021	Lack of Type I Interferon Signaling Ameliorates Respiratory Syncytial Virus-Induced Lung Inflammation and Restores Antioxidant Defenses.
1/2021	Paramyxovirus replication induces the hexosamine biosynthetic pathway and mesenchymal transition via the IRE1α-XBP1s arm of the unfolded protein response.
1/2021	The SWI/SNF-Related, Matrix Associated, Actin-Dependent Regulator of Chromatin A4 Core Complex Represses Respiratory Syncytial Virus-Induced Syncytia Formation and Subepithelial Myofibroblast Transition.
10/2020	Selective Blockade of TNFR1 Improves Clinical Disease and Bronchoconstriction in Experimental RSV Infection.
1/2020	Increased Lung Catalase Activity Confers Protection Against Experimental RSV Infection.
1/2020	HIF-1α Modulates Core Metabolism and Virus Replication in Primary Airway Epithelial Cells Infected with Respiratory Syncytial Virus.
1/2020	A Polymorphism in the Catalase Gene Promoter Confers Protection against Severe RSV Bronchiolitis.
1/2020	Respiratory Syncytial Virus Infection Induces Chromatin Remodeling to Activate Growth Factor and Extracellular Matrix Secretion Pathways.
1/2019	Cystathionine γ-lyase deficiency enhances airway reactivity and viral-induced disease in mice exposed to side-stream tobacco smoke.
11/2018	Exchange Proteins Directly Activated by cAMP and Their Roles in Respiratory Syncytial Virus Infection.

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Roberto P Garofalo Research Topics

Disease

49	Respiratory Syncytial Virus Infections 12/2021 - 05/2002
28	Infections 12/2021 - 06/2002
18	Inflammation (Inflammations) 12/2021 - 05/2002
14	Respiratory Tract Infections (Respiratory Tract Infection) 01/2020 - 05/2003
12	Virus Diseases (Viral Diseases) 12/2019 - 06/2002
10	Lung Diseases (Lung Disease) 01/2021 - 12/2006
10	Bronchiolitis 10/2020 - 06/2004
5	Airway Obstruction (Choking) 12/2021 - 01/2017
5	Pneumonia (Pneumonitis) 12/2021 - 05/2002
3	Body Weight (Weight, Body) 12/2021 - 12/2006
3	Hypoxia (Hypoxemia) 01/2020 - 05/2007
2	Leukemia 12/2021 - 11/2004
2	Lung Injury 01/2020 - 05/2015
2	Airway Remodeling 01/2020 - 06/2017
2	Respiratory Hypersensitivity 01/2019 - 11/2016
1	Bronchopulmonary Dysplasia 01/2020
1	Asthma (Bronchial Asthma) 01/2020
1	Neoplasms (Cancer) 12/2019
1	Weight Loss (Weight Reduction) 01/2018
1	Respiratory Tract Diseases (Respiratory Tract Disease) 10/2017
1	Fibrosis (Cirrhosis) 06/2017
1	Human Influenza (Influenza) 01/2017
1	Viral Pneumonia 11/2016
1	Bone Resorption 01/2016
1	Burns 01/2016

Drug/Important Bio-Agent (IBA)

24	CytokinesIBA 12/2021 - 05/2002
20	ChemokinesIBA 12/2021 - 05/2002
20	Proteins (Proteins, Gene)FDA Link 12/2021 - 06/2002
12	AntioxidantsIBA 12/2021 - 01/2004
12	Antiviral Agents (Antivirals)IBA 01/2018 - 05/2003
11	EnzymesIBA 01/2020 - 09/2009
11	VaccinesIBA 11/2018 - 05/2008
9	Transcription Factors (Transcription Factor)IBA 01/2020 - 05/2008
9	NF-kappa B (NF-kB)IBA 11/2009 - 05/2002
8	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 01/2004
6	InterferonsIBA 12/2017 - 01/2004
4	Interferon Type IIBA 12/2021 - 05/2008
4	CatalaseIBA 01/2020 - 09/2009
4	NF-E2-Related Factor 2IBA 01/2020 - 06/2011
4	Oxygen (Dioxygen)IBA 01/2020 - 10/2008
4	SmokeIBA 01/2020 - 12/2008
4	Interleukin-6 (Interleukin 6)IBA 03/2009 - 12/2005
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2009 - 07/2002
4	Interleukin-8 (Interleukin 8)IBA 08/2008 - 06/2002
4	CC ChemokinesIBA 02/2005 - 05/2002
3	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 10/2017 - 05/2015
3	GYY 4137IBA 01/2017 - 05/2015
3	CXC ChemokinesIBA 01/2017 - 06/2002
3	Phosphotransferases (Kinase)IBA 03/2015 - 08/2002
3	Small Interfering RNA (siRNA)IBA 06/2013 - 02/2007
3	GTP-Binding Proteins (G-Protein)IBA 01/2013 - 05/2008
3	Interferon Regulatory FactorsIBA 05/2008 - 12/2002
3	I-kappa B KinaseIBA 09/2006 - 06/2002
3	Chemokine CCL5IBA 12/2002 - 05/2002
2	ChromatinIBA 01/2021 - 01/2020
2	RNA Polymerase II (RNA Polymerase B)IBA 01/2021 - 01/2018
2	HMGB1 Protein (HMG1)IBA 11/2018 - 11/2016
2	Nuclear Proteins (Protein, Nuclear)IBA 11/2018 - 11/2016
2	Histones (Histone)IBA 01/2018 - 01/2017
2	Cyclin-Dependent Kinase 9IBA 01/2017 - 06/2013
2	Messenger RNA (mRNA)IBA 01/2017 - 11/2009
2	LyasesIBA 11/2016 - 05/2015
2	CystathionineIBA 11/2016 - 05/2015
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 03/2015 - 11/2009
2	Serine (L-Serine)FDA Link 03/2015 - 10/2009
2	Toll-Like Receptors (Toll-Like Receptor)IBA 03/2015 - 09/2013
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 11/2014 - 02/2010
2	RNA (Ribonucleic Acid)IBA 11/2009 - 08/2002
2	Biological ProductsIBA 10/2008 - 03/2004
2	Interferon-alpha (Interferon Alfa)IBA 12/2007 - 08/2005
2	Interleukin-10 (Interleukin 10)IBA 05/2007 - 03/2004
2	ElementsIBA 02/2007 - 01/2004
2	InterleukinsIBA 06/2004 - 06/2002
2	Interferon-gamma (Interferon, gamma)IBA 06/2004 - 01/2004
1	Uridine Diphosphate (UDP)IBA 01/2021
1	HexosaminesIBA 01/2021
1	Glycoproteins (Glycoprotein)IBA 01/2021
1	Activating Transcription Factor 6IBA 01/2021
1	Transaminases (Aminotransferases)IBA 01/2021
1	AcetylglucosamineIBA 01/2021
1	X-Box Binding Protein 1IBA 01/2021
1	Type II Tumor Necrosis Factor ReceptorsIBA 10/2020
1	Type I Tumor Necrosis Factor ReceptorsIBA 10/2020
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 10/2020
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020
1	HexokinaseIBA 01/2020
1	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2020
1	Methacholine Chloride (Methacholine)FDA Link 01/2019
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 01/2018
1	Oxidants (Oxidizing Agents)IBA 01/2018
1	SecretoglobinsIBA 01/2018
1	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2017
1	Interferon LambdaIBA 06/2017
1	Toll-Like Receptor 3IBA 01/2017
1	MucinsIBA 01/2017
1	AcetyltransferasesIBA 01/2017
1	Viral ProteinsIBA 01/2017
1	A-Form DNA (A-DNA)IBA 11/2016

Therapy/Procedure

2	Therapeutics 01/2020 - 11/2016
1	Critical Care (Surgical Intensive Care) 01/2020